DoxyPEP

What Is Doxycycline PEP?

Doxycycline is an antibiotic given for the prevention and treatment of sexually transmitted infections (STI).
STI’s are at an all-time high in the United States
Cisgender males and transgender females who have sex with males taking doxycycline PEP (DoxyPEP) were 70% less likely to be diagnosed with chlamydia and 73% less likely to be diagnosed with syphilis. There was also a 50% decrease in gonorrhea infections.

Who should take DoxyPEP?

Cisgender males and transgender females who have sex with males taking doxycycline PEP (DoxyPEP) were 70% less likely to be diagnosed with chlamydia and 73% less likely to be diagnosed with syphilis. There was also a 50% decrease in gonorrhea infections.
You should continue to be tested for STI’s with your healthcare provider regularly if you are at risk for STI’s

What are the side effects?

Doxycycline is normally well-tolerated by patients who take it to treat an STI
Common side effects include nausea, vomiting, diarrhea, headache, and sun sensitivity of the skin. You should avoid long periods of sun exposure and protect your skin with sunscreen.
Less common side effects include difficulty swallowing, hives, hepatitis (liver inflammation) and low blood counts.
Doxycycline can interact with certain medication such as warfarin, rifampin, systemic retinoids, and some anti-seizure medications.

How do I take DoxyPEP?

Discuss Doxycycline prescription with your healthcare provider.
Take 2 tablets (200 mg), ideally within 24 hours (but no later than 72 hours) after condomless sexual contact.
To minimize side effects, take the medication with at least 8 ounces of water and some food, but not with dairy products like milk. Don’t lie down for one hour after taking the medicine.
Regardless of the number of sexual partners, 200 mg is the maximum dose over 24 hours
You should not take more than 6 tablets in a week.
You should continue to be tested for STI’s with your healthcare provider regularly.